Labcorp is committed to driving the 3Rs agenda and therefore we are continuing to expand and innovate our in vitro testing for the assessment of crop protection products. By partnering with us you will benefit from both our vast experience conducting standard techniques as well as our novel solutions. We’ll create an approach tailored to your regulatory needs and aligned to your substance’s specific properties.
In vitro safety assessments
Multiple in vitro test methods are available for ascertaining the potential impact of your crop protection product on human safety; however how do you find the optimum approach to meet your needs? How can you best exploit in silico and in vitro testing to answer regulatory questions and meet ever-changing endpoints? You need a partner with insight and experience in in vitro test methods and their application to different global regulatory environments..
Labcorp is at the forefront of in vitro testing for crop protection products
Labcorp has played a role in validating various in vitro technologies. Staff engage proactively with the in vitro scientific community via membership of a range of professional bodies such as the in vitro toxicology society (IVTS), in vitro testing industrial platform (IVTIP) and the European Society of Toxicology In Vitro (ESTIV).
This puts us at the forefront of in vitro methodologies and innovations, generating insights that benefit you as our partner.
Partner with an expert team dedicated to delivering in vitro testing success
The in vitro testing team comprises experts from varied backgrounds with extensive experience in planning and managing in vitro tests. The team includes toxicologists, biologists, analytical chemists and environmental scientists. By working collaboratively, study plans can be flexed and optimized to meet your needs and timelines.
Let Labcorp leverage their extensive in vitro testing capabilities to reliably characterize the safety profile of your crop protection product
We conduct approximately 400 in vitro toxicology studies each year covering the following:
Phototoxicity |
Balb/c 3T3 |
OECD 432 |
---|---|---|
Cytotoxicity |
Balb/c; L929; MRC5 |
ISO/ICCVAM/HC |
Skin Corrosion |
3D models |
OECD 431 |
Corrositex® |
OECD 435 |
|
Skin Irritation |
3D models |
OECD 439 |
Eye Irritation |
BCOP |
OECD 437 |
Isolated Chicken Eye Test (with optional histopathology) |
OECD 438 |
|
EpiOcular™ |
OECD 492 |
|
Skin Sensitization |
Direct Peptide Reactivity Assay (DPRA) |
OCED 442C |
KeratinoSens™ Assay |
OCED 442D |
|
Human Cell Line Activation Test (hCLAT) |
OCED 442E |
|
Endocrine Disruption | Estrogen receptor agonist/antagonist |
OECD 455 |
H295R Steroidogenesis assay |
OECD 456 | |
Androgen receptor (AR Calux®) agonist/antagonist | OECD 458 | |
Human Recombinant Estrogen Receptor (hrER) |
OECD 493 |
*In vivo skin sensitisation (OECD 429) can be offered when justified